ABSTRACT
Hepatitis B Virus (HBV) infection is a menace worldwide as a major cause of morbidity & mortality through its consequences viz. acute hepatitis, chronic active, or persistent hepatitis, cirrhosis of liver and primary hepatocellular carcinoma. A total of 127 'HBsAg positive' patients were studied for 'HBeAg' by serum ELISA. Patient's aged between 11 to 60 years with a mean age 27.11. Out of 127 'HBsAg positive' cases 19 (14.96%) were 'HBeAg positive', of which maximum (21.43%) were among <20 years age group. Among 106 male patients 15 (14.155) & among 21 female patients 4 (19.055) were 'HBeAg positive'. Often the initiation of therapeutic approach remains a dilemma in absence of laboratory assessment of viraemic load or presence of HBV DNA through PCR or other DNA hybridization techniques. In such situations, alternatively, a significantly serum 'HBeAg' among 'HBsAg positive' patients may be taken as a surrogate marker for acute viral replication, and, thus apply justifying the initiation of antiviral chemotherapy without delay.
ABSTRACT
H. pylori infection occurs worldwide. Approximately 50% of the world population is infected with this organism. A cross-sectional study was conducted on 81 dyspeptic patients attending at Dhaka Medical College Hospital, for diagnostic endoscopy. H. pylori infection was measured by three invasive methods: culture, rapid urease test & histopathology. Among study patients maximum (34.57%) H. pylori infected were in 21-30 years age group, bearing male female ratio 1: 92.86. Forty four (54.32%) out of 81 were culture positive, 61 (75.31%) were rapid urease test positive and 62 (76.54%) were histopathology positive. By using ‘gold standard’ definition, 64 (79.02%) were H. pylori infected, 17 were un-infected. Finally comparing among three invasive methods, all are highly sensitive and specific to diagnose H. pylori infection.
ABSTRACT
Bone marrow examination of 177 cases of suspected hematological disorders was carried out in a private hospital at Faridpur from May 2007 to August 2009. Among the malignant hematological disorders, Acute Myeloid Leukemia (AML) was the most common disorders (27.69%) followed by Acute Lymphoblastic Leukemia (9.04%), MDS (7.91%), CML (7.34%) and Multiple Myeloma (1.69%). Among the non-malignant hematological disorders, Combined (both iron and folic acid and /or Vitamin B12) deficiency anemia was the most common disorders (24.87%) followed by Aplastic anemia (10.74%), ITP (6.21%), and Kala-azar (2.82%).